Muscadines are known as the “Smarter Grape”. They contain an additional set of chromosomes that other grapes don’t have. These extra genes allow it to create a phytochemical profile with a broader and unique range of nutraceutical potential that is virtually absent in other grapes.
Muscadines contain a staggering number of biomedically active phytonutrients with well known beneficial effects. Below is a list of some of the phytonutrients in Muscadines*:
Ellagic Acid Quercetin Resveratrol Tartaric Acid Chlorogenic Acid Cyanidin Caffeic Acid Peonidin Cinnamic Acid Delphinidin Epicatechin		Petunidin Gallic Acid Malvidian Geraniol Pectin Coumaric Acid Vitamin C Kaempferol Anthocyanidins Myricetin OPCs Oligometric Procyanidins
* As reported in the book Muscadine Medicine by Hartis, Greenspan & Hargrove.

Muscadine Grapes are the #1 Antioxidant Fruit!

+ Oxygen Radical Absorbance Capacity (ORAC) is a test tube analysis that measures the total antioxidant power of foods and other chemical substances. Source: USDA (1999).
* Source: The University of Georgia – College of Agriculture and Environmental Sciences – Dept of Food Science and Technology (2000).
** Source: Brunswick Laboratories (2005 & 2006).

Muscadine Medicine, written by three biomedical researchers who direct nutraceutical research laboratories at the University of Georgia (Diane K. Hartle, Ph.D., Phillip Greenspan, Ph.D. and James L. Hargrove, Ph.D) cites 482 biomedical research papers from top scientific and medical journals concerning the nutraceutical value of  American muscadines and scuppernongs (Vitis rotundifolia). 

Muscadines are the only horticultural crop that originated solely in the United States and are now grown commercially solely in SE USA.  The muscadine is a hardy grape with 20 pairs of chromosomes instead of 19 pairs of chromosomes for other types of grapes. This large amount of extra genetic material may account for its greater range of nutraceutically powerful phytochemicals. The authors summarize and explain the bioactivities of the phytochemicals in muscadines as they relate to preventing heart disease, high cholesterol, prediabetes, diabetes, metabolic syndrome, inflammatory diseases.
 
Gastrointestinal health benefits and longevity are also discussed relevant to muscadine phytochemistry. New nutraceutical products derived from the muscadine arrived in 2005. Muscadine Medicine reviews the scientific literature concerning health benefits of these supplement products and also supports the health benefits of muscadine wines, juice, food products and cosmetic products. Since muscadines are largely known only in SE USA,  this book will prove educational to the nutraceutical community as these products appear on the worldwide market.